The mycinamicins are a new family of basic 16-membered macrolide antibiotics with novel skeletons1,2). During the isolation and purification of mycinamicins I (1), II (2), III (3), IV (4), and V (5) from the culture filtrate of Illicromonospora griseorubida sp. nov., we have discovered two new minor components designated mycinamicin VI (6) and VII (7). Compounds 6 and 7 like 1-53) possess strong antibacterial activity against Gram-positive bacteria. In this paper, the structural characterizations of 6 and 7 are presented.