<jats:title>Abstract</jats:title><jats:p>Two alkaloids, oleraceins F and G, were isolated from <jats:italic>Portulaca oleracea</jats:italic> L., and their structures were determined as methyl (2<jats:italic>S</jats:italic>)‐6‐[(<jats:italic>β</jats:italic>‐<jats:sc>D</jats:sc>‐glucopyranosyl)oxy]‐2,3‐dihydro‐5‐hydroxy‐1‐[(2<jats:italic>E</jats:italic>)‐3‐(4‐hydroxy‐3‐methoxyphenyl)prop‐2‐enoyl]‐1<jats:italic>H</jats:italic>‐indole‐2‐carboxylate and methyl (2<jats:italic>S</jats:italic>)‐6‐[(<jats:italic>β</jats:italic>‐<jats:sc>D</jats:sc>‐glucopyranosyl)oxy]‐2,3‐dihydro‐5‐hydroxy‐1‐[(2<jats:italic>E</jats:italic>)‐3‐(4‐hydroxyphenyl)prop‐2‐enoyl]‐1<jats:italic>H</jats:italic>‐indole‐2‐carboxylate, based on their spectroscopic data. Oleraceins F and G exhibited scavenging activity against 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) radical, with <jats:italic>EC</jats:italic><jats:sub>50</jats:sub> values of 21.00 and 37.69 μ<jats:sc>M</jats:sc>, respectively.