Artemisia monosperma afforded four flavonoids, two acetylenes, eight p-hydroxyacetophenone derivatives and three p-coumaric acid derivatives, two of them being new. The structures were elucidated by spectral methods. The flavonoids present are naringenin 7-methyl ether, eriodictyol 7-methyl ether, quercetin 3,7-dimethyl ether and quercetin 7,3'-dimethyl ether.