The formation of 3-hydroxy-4-methoxyphenylalanine and 3-hydroxy-4-methoxyphenethylamine in plasma during L-DOPA therapy in patients with parkinson's disease.

Chemical and Pharmaceutical Bulletin
1984.0

Abstract

After oral administration of L-3, 4-dihydroxyphenylalanine to patients with Parkinson's disease, 3-hydroxy-4-methoxyphenylalanine and 3-hydroxy-4-methoxyphenethylamine were identified as plasma metabolites, by high performance liquid chromatograph with fluorimetric detection.

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