Flustramines A and B, two bromo-substituted alkaloids, were isolated from the marine bryozoan Flustra foliacea. The isolation procedure and detailed assignment of all ¹³C and ¹H NMR data are reported. Nuclear Overhauser enhancement, difference spectroscopy reveals the pyrrolidine rings to be cis fused, in close analogy with physostigmine. In this paper we wish to report the detailed isolation procedure and structural assignments of flustramines A (1) and B (2), two brominated alkaloids referable to the basic physostigmine skeleton known from the minor group of alkaloids from Calabar bean (Physostigma venenosum Balf. of family Leguminosae).