Twenty-three alkaloids were isolated from leaves and stem bark of Ervatamia polyneura, four of which are new: vobasenal, 16-epivobasenal, 3-oxo-19-epiheyneanine and 3-hydroxy-3,4-secocoronaridine. The other alkaloids are the known pericyclivine, vobasine, vobasine N-(4)-oxide, 16-epivobasine, vobasinol, dregamine, perivine, anhydrovobasindiol, apparicine, (+) tubotaïwine, voaphylline, 3, 14-dihydroellipticine, coronaridine, eglandine, eglandulosine, heyneanine, 19-epiheyneanine, voacangine and coronaridinehydroxyindolenine. Structural elucidation of the new alkaloids was based on spectral data. © 1990.