Three New Cytotoxic Sesterterpenes from the Marine Sponge Hyrtios cf. erectus

Journal of Natural Products
1996.0

Abstract

Three new cytotoxic sesterterpenes, 1-3, have been isolated from the marine sponge Hyrtios cf. erectus. Their structures have been determined by interpretation of NMR data. They exhibited cytotoxicity against P-388 murine leukemia cells with IC50 values of 0.4-2.1 micrograms/mL.

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