Kanchanamycins, New Polyol Macrolide Antibiotics Produced by Streptomyces olivaceus Tue 4018. I. Taxonomy, Fermentation, Isolation and Biological Activitiest.

The Journal of Antibiotics
1996.0

Abstract

The kanchanamycins, a group of novel 36-membered polyol macrolide antibiotics were detected in the culture filtrate and mycelium of Streptomyces olivaceus Tü 4018 by HPLC-diode-array and HPLC-electrospray-mass-spectrometry screening. The compounds show antibacterial and antifungal activities, and are especially effective against Pseudomonas fluorescens. Besides the kanchanamycin complex, strain Tü 4018 produces the 42-membered macrolactones, oasomycin A and desertomycin A, as well as tryptophan-dehydrobutyrine diketopiperazine and daidzein.

DOI： 10.7164/antibiotics.49.758

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