Deacetylation of mycothiol-derived ‘waste product’ triggers the last biosynthetic steps of lincosamide antibiotics

Chemical Science
2015.0

Abstract

<p>Two homologous pyridoxal 5′-phosphate-dependent enzymes LmbF and CcbF transform the deacetylated <italic>S</italic>-cysteinyl residue of related intermediates in the biosynthesis of lincomycin/celesticetin in different ways.</p>

Knowledge Graph

Similar Paper