From the roots of Salvia prionitis, a novel alkaloid named prioline (1) and a new diterpene, prineoparaquinone (2), were isolated together with taxodione; microstegiol; 8,11,13-dehydroabietane; and 2-isopropyl-8-methyl-3,4-phenanthraquinone. The structures of the new compounds were established by spectroscopic means.