Studies on fungal products. Part XXXIII. Structures of new indoloditerpenes, possible biosynthetic precursors of the tremorgenic mycotoxins, penitrems, from Penicillium crustosum.

Chemical and Pharmaceutical Bulletin
1990.0

Abstract

Along with the tremorgenic mycotoxins, penitrems A (3), B (4), D (6), E (7), and F (8), the minor metabolites 1 and 2 were isolated from the mycelia of Penicillium crustosum THOM, which was found contaminating bread intended for school lunches in Tokyo city. The structures of 1 and 2 were determined on the basis of spectroscopic and chemical investigations. These compounds (1 and 2) might be biosynthetic precursors of penitrems.

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