Penicillium verrucosum var. cyclopium RV 67718 isolated from ground cassava collected in Burundi was cultivated under laboratory conditions to produce the mycotoxin roquefortine C [1] and a new structurally related but previously unpublished metabolite [2]. In addition, the tremorgenic compounds penitrems A and B [3,4] were isolated. The structure of [2] was determined using spectroscopic methods. Comparative analysis of the UV, IR, MS, and NMR spectra of [1] and [2] showed closely related structural similarities and revealed [2] is a formyl version of [1] with the CHO group attached to the indoline nucleus. The production of penitrems A and B [3,4], roquefortine C [1], and related metabolites by P. verrucosum var. cyclopium indicates that this mold is a potential hazard for public health, particularly when it occurs in stored food products.