Determination of abamectin in citrus fruits using SPE combined with dispersive liquid–liquid microextraction and HPLC–UV detection

Journal of Separation Science
2013.0

Abstract

<jats:p>A new pretreatment method, SPE combined with dispersive liquid–liquid microextraction, was proposed for the determination of abamectin in citrus fruit samples for the first time. In this method, fruit samples were extracted by ultrasound‐assisted extraction followed by SPE. Then, the SPE was used as a disperser solvent in the next dispersive liquid–liquid microextraction step for further purification and enrichment of abamectin. The effects of various parameters on the extraction efficiency of the proposed method were investigated and optimized. Good linearity of abamectin was obtained from 0.005 to 10.0 mg/kg for B<jats:sub>1a</jats:sub> and from 0.05 to 10.0 mg/kg for B<jats:sub>1b</jats:sub> with correlation coefficient (<jats:italic>r</jats:italic><jats:sup>2</jats:sup>) of 0.998 for B<jats:sub>1a</jats:sub> and 0.991 for B<jats:sub>1b</jats:sub>, respectively. The LODs were 0.001 and 0.008 mg/kg (S/N = 3) for B<jats:sub>1a</jats:sub> and B<jats:sub>1b</jats:sub>, respectively. The relative recoveries at three spiked levels were ranged from 87 to 96% with the RSD less than 11% (<jats:italic>n</jats:italic> = 3). The method has been successfully applied to the determination of abamectin in citrus fruit samples.

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