14-Acetylnudicaulidine and 18-deoxylycoctonine ? New diterpene alkaloids from Delphinium confusum

Chemistry of Natural Compounds
1989.0

Abstract

We have investigated the epigeal part of Delphinium confusum gathered in the flowering stage in the Kusavlisai gorge, Shakhristan Pass (Tadzhik SSR). Chloroform extraction in a Soxhlet apparatus gave 0.54% of total alkaloids, from which we isolated delphatine [1], base (I) with the composition C26H42NO7, mp 206-208°C (hexane-ether), base (II) with the composition C25H42NO6, mp 73-75°C (hexane-ether), and base (III) with the composition C27H43NO8, mp 115-117°C (hexane-ether). On the basis of IR, PMR, and mass spectral data, base (I) was identified as 14-acetylnudicaulidine, base (II) as 18-deoxylycoctonine (a new natural alkaloid), and base (III) as browniine acetate.

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