The known alkaloids isotalatisidine, nevadensine, delcosine, delsoline, and isobaldine have been isolated form the epigeal part of Delphinium confusum M. Pop., collected in the flowering period, and also a new alkaloid with the composition C24H39NO5, mp 136–137°C (acetone), for which the structure of 14-methylisotalatisidine has been established on the basis of spectral characteristics and of passages from condelphine and isotalatisidine. This is the first time that the alkaloids nevadensine, delcosine, delsoline, isobaldine, and 14-methylisotalatisidine have been isolated from this plant. © 1988, Plenum Publishing Corporation. All rights reserved.