Antiplasmodial activity of compounds isolated from Erythrina caffra

South African Journal of Botany

2016.0

Abstract

Different fractions of the acetone stem bark extract of Erythrina caffra were studied for antiplasmodial activity using a chloroquine-sensitive (CQS) strain of Plasmodium falciparum (NF54). The hexane fraction exhibited the highest antiplasmodial activity (IC50 b 10 μg/mL). Through activity-guided fractionation of the hexane fraction, two known compounds, erythrinasinate B and lupeol, with moderate antiplasmodial activity were isolated.

DOI： 10.1016/j.sajb.2016.05.019

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