Literature

Abstract

<jats:title>Abstract</jats:title><jats:p>Two new unique cytotoxic metabolites, conicaquinones A (<jats:bold>1</jats:bold>) and B (<jats:bold>2</jats:bold>), each possessing a 1,1‐dioxo‐1,4‐thiazine ring, were isolated from the Mediterranean ascidian <jats:italic>Aplidium conicum</jats:italic>. Their structures were established by an extensive spectroscopic analysis. Compounds <jats:bold>1</jats:bold> and <jats:bold>2</jats:bold> exhibited a strong cytotoxicity in vitro against rat glioma cells. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)

DOI： 10.1002/EJOC.200390136

Conicaquinones A and B, Two Novel Cytotoxic Terpene Quinones from the Mediterranean Ascidian Aplidium conicum

European Journal of Organic Chemistry 2003.0

Antitumor Effects of Two Novel Naturally Occurring Terpene Quinones Isolated from the Mediterranean Ascidian Aplidium conicum

Journal of Medicinal Chemistry 2005.0

Isolation and Structure Determination of Aplidinones A–C from the Mediterranean Ascidian Aplidium conicum: A Successful Regiochemistry Assignment by Quantum Mechanical 13C NMR Chemical Shift Calculations

European Journal of Organic Chemistry 2005.0

Synthesis of structurally simplified analogues of aplidinone A, a pro-apoptotic marine thiazinoquinone

Bioorganic & Medicinal Chemistry 2010.0

Meroterpenes from the Ascidian Aplidium aff. densum

Journal of Natural Products 2005.0

Caelestines A−D, Brominated Quinolinecarboxylic Acids from the Australian Ascidian Aplidium caelestis