The alkaloid mixture of Datura suaveolens shows distinct differences compared with that of other tree daturas. Aerial parts contain in addition to hyoscine, apohyoscine, norhyoscine, atropine and noratropine, a relatively high proportion of tigloyl esters-3α,6β-ditigloyloxytropan-7β-ol, 6β-tigloyloxytropan-3α,7β-diol,3α-tigloyloxytropan-6β,7β-diol (meteloidine) and (-)- and (±)-3α-tigloyloxytropan-6β-ol. The roots contain hyoscine, meteloidine, atropine, littorine, 3α-acetoxytropane, 6β-(α-methylbutyryloxy)-3α-tigloyloxytropane, 3α,6β-ditigloyloxytropan-7β-ol, 3α-tigloyloxytropan-6β-ol, tropine and cuscohygrine. Other, as yet uncharacterized, bases are present in the plant. Norhyoscine is a principal alkaloid of the corollas. © 1972.