Antibiotics from gliding bacteria, XLIV. Ambruticins VS: New members of the antifungal ambruticin family from Sorangium cellulosum

Liebigs Annalen der Chemie
1991.0

Abstract

<jats:title>Abstract</jats:title><jats:p>A group of six new antifungal metabolites (ambruticins VS‐1 to ‐5, VS‐3 <jats:italic>N</jats:italic>‐oxide) was isolated from the myxobacterium <jats:italic>Sorangium cellulosum</jats:italic>. They were separated by RP chromatography and identified as (5<jats:italic>S</jats:italic>,6<jats:italic>R</jats:italic>)‐5‐amino‐6‐hydroxypolyangioic acids <jats:bold>1b–e, 2b</jats:bold> and methyl ester <jats:bold>2a</jats:bold> by spectroscopic methods.

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