A new steroidal alkaloid, cycloxobuxoviricine (1), has been isolated from the leaves of Buxus papillosa and its structure determined by spectroscopic methods. Isolation and 13C-nmr spectrum of another alkaloid, buxaminol B (2), not previously reported from the leaves of this plant is also described. In our continuing studies on the leaves of Buxus papillosa C.K. Schnn, Linn. (Buxaceae), we have reported several new alkaloids (1-6). The present investigation describes the isolation and structure elucidation of a new steroidal alkaloid, cycloxobuxoviricine (1). Buxaminol B (2), which has not previously been reported from the leaves of this plant, was also isolated and its 13C-nmr spectrum recorded.