Furodysin Lactone and Pyrodysinoic Acid, New Sesquiterpenes from a Philippines Dysidea Species

Journal of Natural Products
2001.0

Abstract

Chemical investigation of a Dysidea sponge, collected at Siquijor, Philippines, has afforded two new sesquiterpenoid metabolites, which we have termed furodysin lactone (1) and pyrodysinoic acid (2). The known 3,6,11-trihydroxy-9,11-secoergostane-7,24(28)-dien-9-one (3) was also encountered. Structure elucidation of the isolated metabolites involved high-field 2-D NMR spectroscopy including 1H-1H COSY, HSQC, and HMBC.

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