Biologically Active Glycosides from Asteroidea, 37. Glycosphingolipids from the Starfish Luidia maculata, 1 Structure of A New Sulfatide Molecular Species

Abstract

<jats:title>Abstract</jats:title><jats:p>A sulfatide molecular species [LMG‐1 (<jats:bold>1</jats:bold>)] have been obtained from the water soluble lipid fraction of the chloroform/methanol extract of the starfish <jats:italic>Luidia maculata</jats:italic>. On the basis of chemical and spectroscopic findings, the structure of <jats:bold>1</jats:bold> has been elucidated. Negative FAB mass spectrometry provided important information both on the structure of the sugar moiety and on the molecular mass of the sulfatide. <jats:bold>1</jats:bold> is, to the authors' knowledge, new sulfatide molecular species and first sulfatide obtained from starfish. In addition, <jats:bold>1</jats:bold> shows neuritogenic activity toward the rat pheochromocytoma cell line, PC‐12 cell.