<jats:title>Abstract</jats:title><jats:p>Four new ceramide lactosides, luidialactoside A (<jats:bold>1</jats:bold>), B (<jats:bold>3</jats:bold>), C (<jats:bold>4</jats:bold>), and D (<jats:bold>5</jats:bold>) were isolated from the water‐insoluble lipid fraction of the CHCl<jats:sub>3</jats:sub>/MeOH extract of the starfish <jats:italic>Luidia maculata</jats:italic>. The structures of these ceramide lactosides were determined on the basis of chemical and spectroscopic evidence. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)