A new inhibitor of protein kinase C, RK-1409 (7-oxostaurosporine). I. Taxonomy and biological activity.

A new inhibitor of protein kinase C, RK-1409 (7-oxostaurosporine). I. Taxonomy and biological activity. A new inhibitor of protein kinase C, RK-1409 (7-oxostaurosporine). I. Taxonomy and biological activity. A new inhibitor of protein kinase C, RK-1409 (7-oxostaurosporine). II. Fermentation, isolation, physico-chemical properties and structure. A new inhibitor of protein kinase C, RK-1409B (4'-demethylamino-4'-hydroxy-3'-epistaurosporine). A new inhibitor of protein kinase C, RK-1409B (4'-demethylamino-4'-hydroxy-3'-epistaurosporine). A new inhibitor of protein kinase C, RK-286C (4'-demethylamino-4'-hydroxystaurosporine) I. Screening, taxonomy, fermentation and biological activity. MLR-52,(4'-dementhylamino-4',5'-dihydroxystaurosporine), a new inhibitor of protein kinase C with immunosuppressive activity. UCN-01 and UCN-02, new selective inhibitors of protein kinase C. I. Screening, producing organism and fermentation. A Nitro Analogue of Staurosporine and Other Minor Metabolites Produced by a Streptomyces longisporoflavus Strain. Factumycin and Its New Derivative RK-1009 Enhance Threonine-phosphorylation of a 60-kDa Protein in Streptomyces griseus.