Two novel dihydrochalcones, 2',3,4',6'-tetrahydroxy-4-methoxy-3',5-di-(3,3-dimethylallyl)-dihydrochalcone and 2',.3,6'-trihydroxy-4-methoxy-5-(3,3-dimethylallyl)-3',4-(2 '',2 ''-dimethyldihydropyran)-dihydrochalone, have been isolated from fresh fruits of Metrodorea nigra. Stems and leaves showed a similar composition and we have isolated common steroids, simple coumarins, several furocoumarins, furoquinoline alkaloids and a furofuran lignan. From stems, we have also isolated the pentacyclic 6-C-monoterpenyl-5,7-dioxycoumarin, deoxybruceol. Structures of the isolated compounds were elucidated on the basis of spectral data.