The dichloromethane extract of the stem bark of Teclea amaniensis has yielded two novel furoquinoline alkaloids, 5-[3-methylbut-2-enyl]-4,6,7- trimethoxyfuro[2,3-b]quinoline and 6-(2′,3′-epoxy-3-methylbutyl)-5- hydroxyl-4,7-dimethoxyfuro[2,3-b]quinoline, in addition to an acridone alkaloid, 2-hydroxy-1,3-dimethoxy-10-methylacridone. Three known alkaloids, dictamnine, kokusaginine and evoxanthine, and two known triterpenoids, lupeol and lupeol acetate were also isolated. Structures of the new compounds were established by means of NMR spectroscopic and MS data.