The alkaloid composition of the rhizomes of Scopolia curndolicu Jacq. has been investigated and the identification of six alkaloids is reported. Three of these alkaloids have been reported previously and are confirmed in this report. Moreover, the authors report here for the first time the presence of 3-a-tigloyloxytropane in the genus Scopolia; in addition, pseudotropine and cuscohygrine are reported in this plant for the first time. One other alkaloid could not be identified at this time.