<jats:p>Allocryptopine and protopine were isolated from the roots, stalks and leaves of <jats:italic>Bocconia frutescens</jats:italic> L. as the main alkaloids and chelerythrine, sanguinarine, chelirubine (not present in leaves), berberine and coptisine as the minor ones. In addition to this (-)-isocorypalmine and (-)-scoulerine were isolated from leaves and traces of rhoeadine were found in the leaves and stalks. From the quaternary fraction of all three parts of the plant columbamine and (-)-α-canadine methohydroxide were also isolated in the form of iodides.