Turbinamide, a New Selective Cytotoxic Agent from the Mediterranean Tunicate Sidnyum turbinatum

Organic Letters
2001.0

Abstract

A unique cytotoxic metabolite, turbinamide (1), has been isolated from the marine tunicate Sidnyum turbinatum through a bioassay-guided approach. Its structure has been elucidated by an extensive spectroscopic analysis. Turbinamide demonstrated a strong and selective cytotoxic effect against neuronal cells rather than immune system cells. Structure: see text.

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