Two new oxygenated pyrenes, 2,7-dihydroxy-1,8-dimethoxypyrene and 2-hydroxy-1,7,8-trimethoxypyrene, have been isolated, from the stem bark of Tanzanian Uvaria lucida spp. lucida, along with the benzylated dihydroflavones chamanetin, isochamanetin, dichamanetin, uvarinol and isouvarinol, and the carotenoid lutein. 2,7-Dihydroxy-1,8-dimethoxypyrene was also isolated from Ghanaian U. doeringii, together with a potential biogenetic precursor of the pyrenes, 1,2-dihydro-2,9-dihydroxy-10-methoxy-furo[2,3-a]phenanthrene, and most of the benzylated flavanones, which were found in U. lucida spp. lucida. Copyright (C) 1996 Elsevier Science Ltd