Increasing the heterologous production of spinosad in Streptomyces albus J1074 by regulating biosynthesis of its polyketide skeleton

Increasing the heterologous production of spinosad in Streptomyces albus J1074 by regulating biosynthesis of its polyketide skeleton Improvement of Spinosad Production upon Utilization of Oils and Manipulation of β-Oxidation in a High-Producing &lt;b&gt;&lt;i&gt;Saccharopolyspora spinosa&lt;/i&gt;&lt;/b&gt; Strain Engineering of the Spinosyn PKS:  Directing Starter Unit Incorporation Discovery of the butenyl-spinosyn insecticides: Novel macrolides from the new bacterial strain Saccharopolyspora pogona Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa11The DNA sequence reported here was deposited in GenBank under the accession number AY007564. The structure of allosamidin, a novel insect chitinase inhibitor, produced by Streptomyces Sp. Genetic control of polyketide biosynthesis in the genusStreptomyces Alchivemycin A, a Bioactive Polycyclic Polyketide with an Unprecedented Skeleton from <i>Streptomyces</i> sp. Sulfinemycin, a New Anthelmintic Antibiotic: Fermentation, Isolation and Structure Determination. Biosynthesis and Total Synthesis Studies on the Jadomycin Family of Natural Products