Diverse DNA-Cleaving Capacities of the Jadomycins through Precursor-Directed Biosynthesis

Diverse DNA-Cleaving Capacities of the Jadomycins through Precursor-Directed Biosynthesis Biosynthesis and Total Synthesis Studies on the Jadomycin Family of Natural Products Copper-mediated nuclease activity of jadomycin B Identification of JadG as the B Ring Opening Oxygenase Catalyzing the Oxidative C-C Bond Cleavage Reaction in Jadomycin Biosynthesis Eight-Membered Ring-Containing Jadomycins: Implications for Non-enzymatic Natural Products Biosynthesis Eight-Membered Ring-Containing Jadomycins: Implications for Non-enzymatic Natural Products Biosynthesis Jadomycins Derived from the Assimilation and Incorporation of Norvaline and Norleucine Jadomycins Derived from the Assimilation and Incorporation of Norvaline and Norleucine Antimicrobial Activities of Jadomycin B and Structurally Related Analogues The Dynamic Structure of Jadomycin B and the Amino Acid Incorporation Step of Its Biosynthesis