In addition to the alkaloids known previously from this plant, haplofoline and folifine, from the epigeal part of Haplophyllum foliosum we have isolated norgraveoline with mp 288-289°C (decomp. from acetone), and myrtopsine with mp 201-202°C (from chloroform), [α]D-5° (c 0.05; methanol), which were first obtained from Haplophyllum dubium and Myrtopsis sellingii, respectively. We have confirmed by the PMR-spectroscopic method the positions of the substituents in the dihydrofuran ring of myrtopsine suggested previously on the basis of biogenetic considerations. In addition, it has been established that the substituents are present in the trans form. This is the first time that myrtopsine has been detected in plants of the genus Haplophyllum. © 1982 Plenum Publishing Corporation.