Three new potent cytotoxic macrolides closely related to sphinxolide from the new caledonian sponge neosiphonia superstes

Tetrahedron
1993.0

Abstract

Three new macroliies 2-4 have been isolated with sphinxolide 1 from the matins sponge N. slrpersles collected off New Caledonia . The structures of the new compounds were deWmined by interpretation of NMR spectral data as well as by comparison of spectral data with those of 1. These compounds were highly cytotoxic against various human carcinoma cells.

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