A Novel Cytotoxic Macrolide, Superstolide B, Related to Superstolide A, from the New Caledonian Marine Sponge Neosiphonia superstes

Journal of Natural Products
1994.0

Abstract

The structure of a new cytotoxic macrolide, superstolide B [1], isolated from the deep water sponge Neosiphonia superstes, collected off New Caledonia, was elucidated mainly on the basis of nmr data. Compound 1 is closely related to superstolide A [2], a major cytotoxic component isolated from that organism, but lacks the 25-hydroxyl group found in 2 and has a C-24 (C-25)-double bond.

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