Two new cyclic peptides, drymarins A and B, were isolated from the whole plants of Drymaria diandra B1. Their structures were determined by detailed spectroscopic analysis as cyclo(-Phe1-Pro1-Pro2-Pro3-Phe2-Phe3-Val-Ile-Ala-) and cyclo (-Pro1-Phe-Tyr-Pro2-Gly-Leu-).