Aconitum napellus ssp. neomontcinum (Wulfen) Gayer (synonym: A. napellus ssp. castellanum Molero & Blanche and A. napellus ssp. lusitanicum Rouy) (Ranunculaceae) is distributed widely from Central Europe to Western France, as well as in Portugal and in Sweden (2, 3). Some preparations of Aconitum roots have long been used as cardiotonics, febrifuges, sedatives, and anodynes in China and Japan (4, 5). As a common Aconitum species in Europe, A. napellus ssp. neomontanum has been given wide attention. Ten norditerpenoid alkaloids, aconitine, N-deethylaconitine, 3-O-acetylaconitine, neoline, chasmanine, 1,14-O-diacetylneoline, isotalatizidine, delsoline, delcosine, and virescenine, and six diterpenoid alkaloids, songorine, songoramine, 12-epinapelline, 12-epidehydronapelline, 12-epiacetyldehydronapelline, and 15-O-acetyl-12 epinapelline, have been isolated from A. napellus SSp. neomontanum (6—8). A sample of the seeds of A. napellus ssp. neomontanum was collected at an altitude of about 1200 m on the Weissenstein mountain, Solothurn, Switzerland, in October 1993. The voucher specimen (No. 76731-5a, b, c) has been deposited in the herbarium of this laboratory. From the CHCI3-soluble alkaloidal extract of this sample, four norditerpenoid alkaloids, karakoline (1), leroyine (2), neoline (3), and isotalatizidine (4), and one diterpenoid alkaloid, 12-epinapelline (5), have been isolated. Aconitine, virescenine, senbusine A, and songorine have been detected by TLC. Although karakoline (1) has been found in several species of Aconitum and Delphinium (9), it has not been reported previously from species napellus of Aconitum. Leroyine (2) previously has been isolated from Delphinium leroyi only (10). Here is the first report for its occurrence in Aconitum plants.