The vine Stephania venosa Spreng. (Menispermaceae), known in Thailand as "sabu-lead" or blood-soap due to its red latex and used as a bitter tonic, had previous rhizome studies identifying new oxoaporphinium salts (uthongine, thailandine) and 7-hydroxylated aporphines (ayuthianine, sukhodianine). The present study on leaf alkaloids isolated two new alkaloids: the aporphine (-)-O-acetylsukhodianine (1) and the oxoaporphine oxostephanosine (2). (-)-O-Acetylsukhodianine, the first known naturally occurring 7-acetoxylated aporphine, had its structure determined via 200 MHz ¹H-NMR (showing a 3-proton singlet at δ 1.90 for the O-acetyl group, a 1-proton doublet at δ 6.87 for H-7, and absorptions for N-methyl, methoxyl, and methylenedioxy groups) and mass spectrum (molecular ion m/z 397 (C₂₁H₂₃NO₆), base peak m/z 337 from loss of HOAc), with confirmation by acetylation of (-)-sukhodianine (reisolated from leaves) to form the compound identical to 1. Oxostephanosine's structure was established via 200 MHz ¹H-NMR (methylenedioxy absorption at δ 6.39, H-3 singlet at δ 7.22, peaks for H-9/H-10/H-11 at δ 7.09-8.15, and doublets for H-4/H-5 at δ 7.80/8.89 with J=5.2 Hz) and mass spectrum (molecular ion m/z 291 (C₁₆H₁₁NO₄), base peak m/z 263 from loss of CO), confirmed by methylation to the known oxostephanine. Known alkaloids isolated included (-)-crebanine, dehydrocrebanine, (-)-tetrahydropalmatine, (-)-kikemanine, liriodenine, oxocrebanine, (-)-ushinsunine, oxostephanine, and (-)-sukhodianine.