<jats:title>Abstract</jats:title><jats:p>Phytochemical investigation from the stems of <jats:italic>Alibertia edulis</jats:italic> led to the isolation and identification of a new iridoid 6<jats:italic>β</jats:italic>‐hydroxy‐7‐epigardoside methyl ester (<jats:bold>1</jats:bold>) and a new saponin 3<jats:italic>β</jats:italic>‐<jats:italic>O</jats:italic>‐[<jats:italic>α</jats:italic>‐<jats:sc>L</jats:sc>‐rhamnopyranosyl‐(1→2)‐<jats:italic>O‐β</jats:italic>‐<jats:sc>D</jats:sc>‐glucopyranosyl‐(1→2)‐<jats:italic>O‐β</jats:italic>‐<jats:sc>D</jats:sc>‐glucopyranosyl]‐28‐<jats:italic>O‐β‐</jats:italic><jats:sc>D</jats:sc>‐glucopyranoside pomolate (<jats:bold>2</jats:bold>), along with three known compounds, shanzhiside methyl ester (<jats:bold>3</jats:bold>), ixoside (<jats:bold>4</jats:bold>), and 3,4,5‐trimethoxyphenyl 1‐<jats:italic>O</jats:italic>‐<jats:italic>β</jats:italic>‐<jats:sc>D</jats:sc>‐apiofuranosyl‐(1→6)‐<jats:italic>O‐β</jats:italic>‐<jats:sc>D</jats:sc>‐glucopyranoside (<jats:bold>5</jats:bold>). The structures of <jats:bold>1</jats:bold> and <jats:bold>2</jats:bold> were established on the basis of their spectroscopic data. Iridoid <jats:bold>1</jats:bold> and saponin <jats:bold>2</jats:bold> exhibited moderate inhibitory activities against <jats:italic>Candida albicans</jats:italic> and <jats:italic>C. krusei</jats:italic> in a dilution assay.