Halicylindrosides, antifungal and cytotoxic cerebrosides from the marine sponge Halichondria cylindrata

Tetrahedron
1995.0

Abstract

Ten new glycosphingolipids, halicylindrosides AI-A4 (1-4) and BI-B6 (5-10) have been isolated from the Japanese marine sponge Halichondria cylindrata. Their structures were determined by spectroscopic and chemical methods. These cerebrosides were moderately antifungal against Mortierella remanniana, and cytotoxic against P388 murine leukemia cells

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