From the ether-soluble fraction of an extract of Sapium indicum two new nitrogen-containing esters of deoxyphorbol, sapintoxins B and C, were isolated. Both were characterized by the bright blue fluorescence which they exhibited in UV light. Sapintoxin B was identified as 12-(N-methylaminobenzoyl)-4-deoxy-5-hydroxyphorbol-13 acetate and sapintoxin C as 12-(N-methylaminobenzoyl)-4,20-dideoxy-5-hydroxyphorbol-13-acetate.