Four new coumarins, omphalocarpin, (-)-murracarpin, murrayacarpin-A and -B together with known coumarins, scopolin, scopoletin, 5,7-dimethoxy-8-(3'-methyl-2'-oxobutyl)coumarin, (±)-murracarpin and mupanidin have been isolated from the flowers of Murraya paniculata var. omphalocarpa. Their structures have been characterized from spectral analysis, chemical transformation and/or synthesis.