Pyridone and Tetramic Acid Alkaloids from the Spider Pathogenic Fungus Torrubiella sp. BCC 2165

Journal of Natural Products
2010.0

Abstract

Torrubiellones A-D (1-4), new pyridone and tetramic acid alkaloids, were isolated from the spider pathogenic fungus Torrubiella sp. BCC 2165. Torrubiellone A (1) exhibited antimalarial activity with an IC(50) value of 8.1 μM, while it showed very weak cytotoxic activity.

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