Keramamides E, G, H, and J, new cyclic peptides containing an oxazole or a thiazole ring from a Theonella sponge

Tetrahedron
1995.0

Abstract

Four new cyclic peptides, keramamides E (1), G (2), H (3), and J (4), containing an oxazole or a thiazole ring have been isolated from the Okinawan marine sponge Theonella sp. and the structures elucidated by 2D NMR data and degradation experiments. The sequence of amino acid residues in 1 ~ 4 was determined on the basis of FAB MS/MS data.

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