Tolypodiol, an Antiinflammatory Diterpenoid from the Cyanobacterium Tolypothrix nodosa

Journal of Natural Products
1996.0

Abstract

A new diterpenoid, tolypodiol (1), has been isolated from the terrestrial cyanobacterium Tolypothrix nodosa (HT-58-2) and identified by NMR and mass spectral analysis. The monoacetate derivative 2 was prepared. Tolypodiol (1) and its monoacetate derivative 2 show potent antiinflammatory activity in the mouse ear edema assay.

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