Secondary Metabolites from the Sponge Tedania anhelans:  Isolation and Characterization of Two Novel Pyrazole Acids and Other Metabolites

Journal of Natural Products
1997.0

Abstract

Chemical investigation of the methanol extract of the sponge Tedania anhelans yielded the two unusual heteroaromatic acids, pyrazole-3(5)-carboxylic acid (2) and 4-methylpyrazole-3(5) carboxylic acid (3), which are reported for the first time as natural products. The other compounds isolated were p-hydroxybenzaldehyde, phenylacetamide, 3-phenylpropionic acid, 3-(p-hydroxyphenyl)propionic acid, 3-(p-methoxyphenyl)propionic acid, â-carboline (norharman) (1), and the four diketopiperazines pro-val, pro-leu, pro-phe, and pro-tyr.

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