1,19-seco-Avermectin Analogues from a ΔaveCDE Mutant Streptomyces avermectinius Strain

1,19-seco-Avermectin Analogues from a Δ<i>aveCDE</i> Mutant <i>Streptomyces avermectinius</i> Strain Three new milbemycins from a genetically engineered strain S. avermitilis MHJ1011 Isolation of linear peptides related to the hepatotoxins nodularin and microcystins Selective production of specific components of avermectins in Streptomyces avermitilis. Three new 16-membered macrolide compounds from a genetically engineered strain S . avermitilis MHJ1011 Recent advances in biochemistry and biotechnological synthesis of avermectins and their derivatives Engineering the <i>aveC</i> gene to enhance the ratio of doramectin to its CHC‐B2 analogue produced in <i>Streptomyces avermitilis</i> Gene Replacement for the Generation of Designed Novel Avermectin Derivatives with Enhanced Acaricidal and Nematicidal Activities Production of doramectin by rational engineering of the avermectin biosynthetic pathway Isolation and Characterization of New 16-Membered Macrolides from the <i>aveA3</i> Gene Replacement Mutant Strain <i>Streptomyces avermitilis</i> TM24 with Acaricidal and Nematicidal Activities