A novel alkaloid named bowdichine ( 1 ), only the third with a diaza-adamantane skeleton containing an unusual N -acetyl enamine moiety, and the known alkaloids acosmine ( 2 ), ormosanine ( 3 ) and podopetaline ( 4 ) have been isolated from the stem bark of Bowdichia virgilioides . The structures were elucidated on the basis of spectral data, mainly 1D and 2D NMR of the diaza-adamantane alkaloids 1 and 2 .