A novel 3 alpha,6 beta,7 beta-triol tropane alkaloid esterified by two benzoyl residues was isolated from the leaves of the endemic cuban species, Erythroxylon alaternifolium. Another novel 3 alpha,6 beta,7 beta-triol tropane alkaloid esterified by trimethoxycinnamoyl and trimethoxybenzoyl residues was isolated from the leaves and stem bark of a second endemic cuban species, Erythroxylon rotundifolium. Their structures were elucidated as 3 alpha,7 beta-dibenzoyloxy-6 beta-hydroxy-tropane and 3 alpha-(3,4,5-trimethoxycinnamoyloxy)-7 beta-(3,4,5-trimethoxybenzoyloxy)-6 alpha-hydroxy-tropane by spectroscopic methods including 2D-NMR techniques. (C) 2000 Elsevier Science Ltd. All rights reserved.