Xantholipin, a novel inhibitor of HSP47 gene expression produced by Streptomyces sp.

Tetrahedron Letters
2003.0

Abstract

In the course of our screening program to identify inhibitors of HSP47 gene expression, we obtained a novel aromatic substance from Streptomyces sp. named Xantholipin. Its structure was determined based on physicochemical data of Xantholipin and its derivatives. The absolute configuration was also established by the modified Mosher's method.

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